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You can explore research tailored to your specific health interests and needs. Discover the science-backed benefits of CBD across various applications, helping you make informed decisions about incorporating CBD into your wellness routine.
Key Insights and Research
In the midst of CBD's rising popularity, there remains a notable gap in people's understanding of its true benefits. Despite the growing recognition of its potential, there's still much to explore. At our core, we genuinely care about our customers and place a strong emphasis on education. It's our commitment to keep you well-informed about cannabidiol, providing easy access to the latest and most credible research findings.To ensure that you stay abreast of the evolving landscape, we actively update our comprehensive database. This repository houses research conducted on CBD, allowing you to make informed decisions about your well-being. Your trust is paramount to us, and we strive to empower you with the knowledge you need for a holistic understanding of CBD's benefits.
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- Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors
- Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors
- Cannabidiol reduces cigarette consumption in tobacco smokers: preliminary findings
- Early Phase in the Development of Cannabidiol as a Treatment for Addiction: Opioid Relapse Takes Initial Center Stage
- Cannabidiol as an Intervention for Addictive Behaviors: A Systematic Review of the Evidence
- Cannabidiol for the Reduction of Cue-Induced Craving and Anxiety in Drug-Abstinent Individuals With Heroin Use Disorder: A Double-Blind Randomized Placebo-Controlled Trial
- Unique treatment potential of cannabidiol for the prevention of relapse to drug use: preclinical proof of principle
- Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain
- Cannabidiol treatment in an adolescent with multiple substance abuse, social anxiety and depression
- Cannabidiolic acid methyl ester, a stable synthetic analogue of cannabidiolic acid, can produce 5-HT1A receptor-mediated suppression of nausea and anxiety in rats
- Cannabidiol regulation of emotion and emotional memory processing: relevance for treating anxiety-related and substance abuse disorders
- Cannabidiol Does Not Dampen Responses to Emotional Stimuli in Healthy Adults
- Effect of prior foot shock stress and Δ9-tetrahydrocannabinol, cannabidiolic acid, and cannabidiol on anxiety-like responding in the light-dark emergence test in rats
- Inverted U-Shaped Dose-Response Curve of the Anxiolytic Effect of Cannabidiol during Public Speaking in Real Life
- Cannabidiol regulation of emotion and emotional memory processing: relevance for treating anxiety-related and substance abuse disorders
- Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report
- Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor
- Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa
- The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system
- Does Cannabidiol Protect Against Adverse Psychological Effects of THC?
- Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug
- The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system
- Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients
- Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report
- Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients
- Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report
- Distinct effects of {delta}9-tetrahydrocannabinol and cannabidiol on neural activation during emotional processing
- Effects of cannabidiol (CBD) on regional cerebral blood flow
- Endocannabinoids, cannabinoids and the regulation of anxiety
- Cannabidiol as a Potential Treatment for Anxiety Disorders
- Striking lung cancer response to self-administration of cannabidiol: A case report and literature review
- Cannabidiol-induced apoptosis is mediated by activation of Noxa in human colorectal cancer cells
- Concomitant Treatment of Malignant Brain Tumours With CBD - A Case Series and Review of the Literature
- Report of Objective Clinical Responses of Cancer Patients to Pharmaceutical-grade Synthetic Cannabidiol
- Cannabidiol rather than Cannabis sativa extracts inhibit cell growth and induce apoptosis in cervical cancer cells
- Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol
- Cannabidiol as potential anticancer drug
- Cannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect
- Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents
- An open-label extension study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics
- Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms
- COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells
- Cannabidiol as potential anticancer drug
- Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpesvirus-infected endothelium
- Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1
- Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpesvirus-infected endothelium
- Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer
- Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy
- Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis
- Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy
- Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain
- Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival
- A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cells
- Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
- Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma
- Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression
- Gamma-irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells
- Cannabidiol Effectively Promoted Cell Death in Bladder Cancer and the Improved Intravesical Adhesion Drugs Delivery Strategy Could Be Better Used for Treatment
- The Pathophysiology and the Therapeutic Potential of Cannabinoids in Prostate Cancer
- Cannabidiol directly targets mitochondria and disturbs calcium homeostasis in acute lymphoblastic leukemia
- Cannabinoids as therapeutic agents in cancer: current status and future implications
- Cannabinoids Induce Cancer Cell Proliferation via Tumor Necrosis Factor α-Converting Enzyme (TACE/ADAM17)-Mediated Transactivation of the Epidermal Growth Factor Receptor
- Cannabinoids for Cancer Treatment: Progress and Promise
- The Atypical Cannabinoid Abn-CBD Reduces Inflammation and Protects Liver, Pancreas, and Adipose Tissue in a Mouse Model of Prediabetes and Non-alcoholic Fatty Liver Disease
- Cannabidiol attenuates mechanical allodynia in streptozotocin-induced diabetic rats via serotonergic system activation through 5-HT1A receptors
- Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study
- Cannabidiol improves vasorelaxation in Zucker diabetic fatty rats through cyclooxygenase activation
- Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy
- Cannabidiol arrests onset of autoimmune diabetes in NOD mice
- Cannabidiol lowers incidence of diabetes in non-obese diabetic mice
- Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes
- Cannabidiol (CBD) and cognition in epilepsy
- Cross-sectional and longitudinal evaluation of cannabidiol (CBD) product use and health among people with epilepsy
- UHPLC-MS/MS Analysis of Cannabidiol and Its Metabolites in Serum of Patients with Resistant Epilepsy Treated with CBD Formulations
- The results of this multicenter study on CBD treatment for intractable epilepsy in a population of children and adolescents are highly promising. Further prospective, well-designed clinical trials using enriched CBD medical cannabis are warranted.
- Anticonvulsive Properties of Cannabidiol in a Model of Generalized Seizure Are Transient Receptor Potential Vanilloid 1 Dependent
- Epilepsy and cannabidiol: a guide to treatment
- Cannabidiol in treatment of refractory epileptic spasms: An open-label study
- The proposed mechanisms of action of CBD in epilepsy
- Dose-Ranging Effect of Adjunctive Oral Cannabidiol vs Placebo on Convulsive Seizure Frequency in Dravet Syndrome: A Randomized Clinical Trial
- Cost-effectiveness of cannabinoids for pediatric drug-resistant epilepsy: protocol for a systematic review of economic evaluations
- Update on Antiepileptic Drugs 2019
- Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional antiepileptic treatment on seizure frequency in dogs with intractable idiopathic epilepsy
- Food effect on pharmacokinetics of cannabidiol oral capsules in adult patients with refractory epilepsy
- Cannabis-based products for pediatric epilepsy: A systematic review
- Long-term cannabidiol treatment in patients with Dravet syndrome: An open-label extension trial
- Cannabidiol in patients with Lennox-Gastaut syndrome: Interim analysis of an open-label extension study
- Drug-drug interactions with cannabidiol (CBD) appear to have no effect on treatment response in an open-label Expanded Access Program
- Long-Term Safety, Tolerability, and Efficacy of Cannabidiol in Children with Refractory Epilepsy: Results from an Expanded Access Program in the US
- Pharmacological and Therapeutic Properties of Cannabidiol for Epilepsy
- Quality of life in adults enrolled in an open-label study of cannabidiol (CBD) for treatment-resistant epilepsy
- Potential Clinical Benefits of CBD-Rich Cannabis Extracts Over Purified CBD in Treatment-Resistant Epilepsy: Observational Data Meta-analysis
- Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial
- Cannabidiol for Treatment of Childhood Epilepsy-A Cross-Sectional Survey
- Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut Syndrome
- Interactions between cannabidiol and commonly used antiepileptic drugs
- Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome
- Historical perspective on the medical use of cannabis for epilepsy: Ancient times to the 1980s
- CBD-enriched medical cannabis for intractable pediatric epilepsy: The current Israeli experience
- Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial
- Cannabinoids and Epilepsy
- Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
- Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability
- Drug-drug interaction between clobazam and cannabidiol in children with refractory epilepsy
- Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo
- Downregulation of the CB1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus
- Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: a role for A2A receptors
- A double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis
- Nabiximols (THC/CBD oromucosal spray, Sativex®) in clinical practice--results of a multicenter, non-interventional study (MOVE 2) in patients with multiple sclerosis spasticity
- Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells
- Daily Practice Managing Resistant Multiple Sclerosis Spasticity With Delta-9-Tetrahydrocannabinol: Cannabidiol Oromucosal Spray: A Systematic Review of Observational Studies
- Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: a role for A2A receptors
- Symptomatic therapy in multiple sclerosis: the role of cannabinoids in treating spasticity
- A placebo-controlled, parallel-group, randomized withdrawal study of subjects with symptoms of spasticity due to multiple sclerosis who are receiving long-term Sativex® (nabiximols)
- Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice
- Meta-analysis of the efficacy and safety of Sativex (nabiximols), on spasticity in people with multiple sclerosis
- Cannabinoids in the management of spasticity associated with multiple sclerosis
- Oromucosal delta9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: an uncontrolled, open-label, 2-year extension trial
- Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain
- Cannabinoid control of neuroinflammation related to multiple sclerosis
- Sativex: clinical efficacy and tolerability in the treatment of symptoms of multiple sclerosis and neuropathic pain
- An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis
- The cannabinoids: an overview. Therapeutic implications in vomiting and nausea after cancer chemotherapy, in appetite promotion, in multiple sclerosis and in neuroprotection
- Effect of combined oral doses of Δ(9)-tetrahydrocannabinol (THC) and cannabidiolic acid (CBDA) on acute and anticipatory nausea in rat models
- Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT1A receptor activation
- Suppression of lithium chloride-induced conditioned gaping (a model of nausea-induced behaviour) in rats (using the taste reactivity test) with metoclopramide is enhanced by cannabidiolic acid
- Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus
- Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews
- The effects of cannabidiol and tetrahydrocannabinol on motion-induced emesis in Suncus murinus
- Cannabidiol, a non-psychoactive component of cannabis and its synthetic dimethylheptyl homolog suppress nausea in an experimental model with rats
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